High Dose Vitamin C

Ascorbic acid (Vitamin C) plays an important role in many physiological processes, and is an essential nutrient for immune function. The human body does not naturally produce vitamin c, meaning it must be absorbed through diet or supplementation. A maximum of 1000 mg may be absorbed through oral supplementation per hour. IV administration guarantees 100% absorption of up to 75,000 mg at a time.

Intravenous vitamin c can be used as an effective and natural cancer recovery therapy. Recent studies have shown that vitamin c increases the effectiveness of conventional oncology treatment: including chemotherapy and radiation. IV vitamin c can reduce or even eliminate the negative side effects often experienced by patients undergoing chemotherapy, such as weight loss and a weakened immune system. It has also been shown to prolong survival, increase quality of life, and inhibit metastasis (spreading) of cancer. Testing has shown that these results are impossible to achieve through oral supplementation of vitamin c, indicating the importance of intravenous administration.

Conditions Regularly Treated:

  • Cancer Support Therapy
  • Immune Therapy

Sampling of Clinical Research

Ewan Cameron and Linus Pauling. The Orthomolecular Treatment of Cancer I: The role of ascorbic acid in host resistance. Chemico-Biological Interactions. Volume 9, Issue 4, October 1974, Pages 273-283.

Sebastian J. Padayatty, Hugh D. Riordan, Stephen M. Hewitt, Arie Katz, L. John Hoffer and Mark Levine. Intravenously Administered Vitamin C as Cancer Therapy: Three cases. Research. Volume 174, Issue 7, March 28, 2006, Pages 937-942.

Qi Chen, Michael Graham Espey, Murali C. Krishna, James B. Mitchell, Christopher P. Corpe, Garry R. Buettner, Emily Shacter, and Mark Levine. Pharmacologic Ascorbic Acid Concentrations Selectively Kill Cancer Cells: Action as a pro-drug to deliver hydrogen peroxide to tissues. Proceedings of the National Academy of Sciences. Volume 102, Issue 38, September 20, 2005, Pages 13604–13609.

Qi Chen, Michael Graham Espey, Andrew Y. Sun, Je-Hyuk Lee, Murali C. Krishna, Emily Shacter, Peter L. Choyke, Chaya Pooput, Kenneth L. Kirk, Garry R. Buettner, and Mark Levine. Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo. Proceedings of the National Academy of Sciences. Volume 104, Issue 21, May 22, 2007, Pages 8749–8754.

Qi Chen, Michael Graham Espey, Andrew Y. Sun, Chaya Pooput, Kenneth L. Kirk, Murali C. Krishna, Deena Beneda Khosh, Jeanne Drisko, and Mark Levine. Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Proceedings of the National Academy of Sciences. Volume 105, Issue 32, August 12, 2008, Pages 11105–11109.

Anderson P., Nadis E., Standish L. (2011, November). High Dose IV Ascorbic Acid Therapy: the Bastyr Experience. Poster session presented at the Society for Integrative Oncology, Cleveland, OH.

Yeom CH Jung GC, Song KJ. Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration. J Korean Med Sci. 2007 Feb;22(1):7-11.

Vollbracht C, et. al. Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-/radiotherapy and aftercare: results of a retrospective, multicentre, epidemiological cohort study in Germany. In Vivo. 2011 Nov-Dec;25(6):983-90.

Vojdani, A. Namatella, G. Enhancement of Human Natural Killer Cytotoxic Activity by Vitamin C in Pure and Augmented Formulations. Journal of Nutritional and Environmental Medicine. Vol. 7, No. 3 , Pages 187-196. 1997. DOI:10.1080/13590849762600

Lutsenko, E A, Carcamo J M, Golde DW. Vitamin C Prevents Gene Mutation Induced by Oxidative Stress. Journal of Biological Chemistry. 277(19), May10,2002. DOI 10.1074/jbc.M201151200 / available online at http://www.jbc.org

Fromberg, A, et.al. Ascorbate Exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs. Cancer Chemother Pharmacol, 67:1157-1166, 2011. DOI 10.1007/s00280-010-1418-6 (Springer online).

Chen P, Stone J, Sullivan G, Drisko JA, Chen Q. Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models. Free Radic Biol Med. 2011 May 30. PMID: 21672627

Gonzalez, MJ, et.al. Orthomolecular Oncology Review: Ascorbic Acid and Cancer 25 Years Later. Integrative Cancer Therapies 4[1]; 2005 32-44 DOI: 10.1177/1534735404273861

Ma, Y. et. al. (2011, November). Vitamin C and Lung Cancer: A Systematic Review. Moderated Abstract [49] presented at the Society for Integrative Oncology, Cleveland, OH.


Meet With A Doctor

The easiest way to get started is to schedule a free 15 minute coordination meeting to discuss what lab tests will help meet your health goals and whether we can run these tests through your insurance provider.