As a hydrogen bond disruptor, Dimethyl sulfoxide (DMSO) diminishes inflammation by reducing free radicals and preventing the oxidation of lipoproteins. DMSO is not naturally produced and must be obtained through supplementation. Dimethyl sulfoxide (DMSO) is metabolically converted to Methylsulphonylmethane (MSM) within the body. MSM is a sulfur compound that is essential for all bodily systems and normal organ functions. Although naturally occurring, MSM is easily destroyed by constant utilization and excretion.

DMSO and MSM have been used for many years by athletes to treat painful muscles and joints. They are also beneficial for the healing of wounds due to their ability to act therapeutically as an anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal.

Conditions Regularly Treated:

  • Arthritis
  • Chronic Pain/ Inflammation
  • Closed Head Injuries
  • TIA
  • Stroke
  • Immune Stimulant

Sampling of Clinical Research

Tschope, M., cited in Raettig, H. “The potential of DMSO in experimental immunology,” Dimethylsulfoxyl, Internationales Symposium in Wien. G. Laudahn and K. Getrich, eds.; 54. Saladruck, Berlin, Germany, 1966.

Lubredo, L., Barrie, M.S., Woltering, E.A. DMSO protects against adriamycin-induced skin necrosis. J. Surg Res 53:62-65, 1992.

MSM: the definitve guide. A Comprehensive Review of the Science and Therapeutics of methylsulfonylmethane. Stanley Jacob, MD and Jeremy Appleton, ND. Freedom Press, Topanga, CA, 2003.

Julian T. Hoff, Richard F. Keep, Guohua Xi and Ya Hua. Effect of dimethyl sulfoxide on blood-brain barrier integrity following middle cerebral artery occlusion in the rat. Acta Neurochirurgica Supplementum–Brain Edema XIII 10.1007/3-211-30714-1_55.

Szmant, H. Harry. Physical properties of dimethyl sulfoxide and its function in biological systems, Biological Actions of Dimethyl Sulfoxide ed. by Stanley W. Jacob and Robert Herschler. (New York: New York Academy of Sciences, 1975), pp. 20-23.

Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006;14(3):286–94. PMID 16309928.


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